| Cover | | Date  | Title • Artist  Album | Points  | Charts Peaks | Comment |
|---|
 | 1. | 10/1988 | | 516
 | US 3 UK ✫1 US dance 37 US rock ✫1 US alt. ✫1 | [Island 7-99250] written by Bono, The Edge, Adam Clayton & Larry Mullen Jr. |
 | 2. | 10/1988 | | 382
 | US 14 UK 9 US AC 38 US rock ✫1 US alt. 3 | [tribute to Billie Holiday] [Island 7-99254] written by Bono, The Edge, Adam Clayton & Larry Mullen Jr. |
 | 3. | 11/1988 | | 353
 | UK 28 US rock ✫1 US alt. ✫1 | written by Bill Berry, Peter Buck, Mike Mills & Michael Stipe |
 | 4. | 06/1988 | | 310
 | US ✫1 UK 53 US AC ✫1 US dance 21 US R&B 30 US rock ✫1 | [Atco 99326 (Virgin)] written by Steve Winwood, Will Jennings, Brian Holland, Lamont Dozier & Eddie Holland Jr. |
 | 5. | 09/1988 | | 291
 | US 7 UK 31 US AC 30 US rock 9 US alt. 4 | as Edie Brickell & New Bohemians written by Edie Brickell & Kenny Withrow |
 | 6. | 07/1988 | | 268
 | US ✫1 UK 11 US rock 3 | [Polygram 870402 (Mercury)] written by Joe Elliott, Phil Collen, Steve Clark, Rick Savage & Robert John "Mutt" Lange |
 | 7. | 10/1988 | | 265
 | US 68 UK 6 US rock 2 US alt. 10 | with B.B. King [Island 7-99225] written by Bono, The Edge, Adam Clayton & Larry Mullen Jr. |
 | 8. | 04/1988 | | 257
 | US 5 UK 44 US AC ✫1 US rock ✫1 | [RCA 7645] written by Bruce Hornsby & John Hornsby |
| 9. | 06/1988 | | 257
 | US 2 UK 44 US rock ✫1 | [EMI-Manhattan 50133] written by Robert Palmer |
 | 10. | 09/1988 | | 255
 | US ✫1 UK 17 US rock 3 | [Polygram 870657 (Mercury)] written by Jon Bon Jovi, Richie Sambora & Desmond Child |
 | 11. | 01/1988 | | 252
 | US 6 UK 27 US rock ✫1 | [Warner 28119] written by David Lee Roth & Brett Tuggle |
| 12. | 06/1988 | | 249
 | US 5 UK 28 US rock ✫1 | [Warner 27827] written by Michael Anthony, Sammy Hagar, Eddie Van Halen & Alex Van Halen |
| 13. | 07/1988 | | 249
 | US 6 UK 89 US AC 2 US rock ✫1 | [Virgin 7-99290] written by Steve Winwood & Will Jennings |
| 14. | 12/1988 | | 242
 | US 6 UK 48 US alt. ✫1 | [R] [Warner 27688] written by Bill Berry, Peter Buck, Mike Mills & Michael Stipe |
 | 15. | 06/1988 | | 238
 | US ✫1 UK 24 US rock 7 | [Rolling Stone 500 Greatest Songs #196] [Geffen 27963] written by Izzy Stradlin, Slash & Axl Rose |
| 16. | 08/1988 | | 237
 | US ✫1 US dance 36 US rock 45 US alt. 3 | [Atlantic 89048] written by The Escape Club |
 | 17. | 04/1988 | | 235
 | US 3 UK 20 US rock 3 | [Polygram 870692 (Mercury)] written by Joe Elliott, Phil Collen, Steve Clark, Rick Savage & Robert John "Mutt" Lange |
 | 18. | 06/1988 | | 232
 | US 7 UK 24 US AC 42 US rock 5 US alt. 28 | [Atlantic 89038] written by Andrew Farriss & Michael Hutchence |
 | 19. | 04/1988 | | 232
 | US ✫1 UK 77 US AC 29 US rock 3 | [Columbia 07745 (Epic)] written by Bob Mitchell & Nick Graham |
 | 20. | 10/1988 | | 230
 | US 24 UK ✫1 US AC 7 US alt. 6 | written by Enya & Roma Ryan |
| 21. | 12/1988 | | 228
 | US 4 UK 10 US rock 7 | written by Izzy Stradlin |
 | 22. | 10/1988 | | 221
 | US ✫1 UK 13 US rock 11 | [Enigma 44203] written by Bobby Dall, C.C. DeVille, Bret Michaels & Rikki Rockett |
 | 23. | 01/1988 | | 220
 | US 3 UK 69 US rock 2 | [Geffen 28249] written by Steven Tyler & Desmond Child |
| 24. | 11/1988 | | 209
 | US 95 UK 55 US rock 6 US alt. 4 | written by Midge Ure |
 | 25. | 10/1988 | | 209
 | US 3 UK 22 US rock 7 | [Polygram 872156 (Mercury)] written by Jon Bon Jovi, Richie Sambora & Desmond Child |
 | 26. | 07/1988 | | 206
 | US 3 UK 48 US AC 2 US rock 5 | [Chrysalis 43265] written by Alex Call |
 | 27. | 01/1988 | | 205
 | US 3 UK 25 US dance 11 US rock 8 | [Atlantic 89080] written by Andrew Farriss & Michael Hutchence |
 | 28. | 05/1988 | | 204
 | US 6 UK 5 US AC 7 US rock 19 | [Rolling Stone 500 Greatest Songs #165] [Elektra 69412] written by Tracy Chapman |
 | 29. | 10/1988 | | 198
 | US 5 UK 35 US alt. 5 | [Columbia 08090] written by Susanna Hoffs, Tom Kelly & Billy Steinberg |
 | 30. | 02/1988 | | 198
 | US 17 UK 6 US dance 20 US rock 6 | [Columbia 38-07433] written by Rob Hirst, James Moginie & Peter Garrett |
 | 31. | 07/1988 | | 192
 | US 53 UK 16 US dance 14 US alt. ✫1 | [Geffen 7-27760] written by Siouxsie & the Banshees, Harry Warren & Johnny Mercer |
 | 32. | 10/1988 | | 192
 | US 9 US rock 2 | [Columbia 08060] written by Jesse Harms |
| 33. | 03/1988 | | 192
 | US 25 UK 87 US rock ✫1 | featuring Jimmy Page [Es Paranza 7-99348] written by Phil Johnstone & Robert Plant |
 | 34. | 06/1988 | | 192
 | US 2 UK 30 US AC ✫1 US dance 7 US rock 13 | [MCA 53345] written by Elton John & Bernie Taupin |
 | 35. | 10/1988 | | 191
 | US 4 UK 14 US dance ✫1 US alt. 13 | [Capitol 44237] written by Nick Rhodes, Simon Le Bon & John Taylor |
| 36. | 07/1988 | | 191
 | US 11 US AC ✫1 US rock 2 | [Atco 99261 (Virgin)] written by Steve Winwood & Will Jennings |
| 37. | 07/1988 | | 182
 | US 19 UK 19 US rock 2 | [Chrysalis 43268] written by Kerryn Tolhurst, Myron Grombacher & Pat Benatar |
| 38. | 01/1988 | | 181
 | UK 33 US rock ✫1 | [Atco 99373 (Es Paranza)] written by David Barratt & Phil Johnstone |
| 39. | 06/1988 | | 179
 | US 13 US rock 2 | [Warner 27746] written by Michael Anthony, Sammy Hagar, Eddie Van Halen & Alex Van Halen |
| 40. | 11/1988 | | 179
 | US 3 US rock 7 | [Atlantic 89015] written by Mike Tramp & Vito Bratta |
| 41. | 10/1988 | | 175
 | US 14 UK 4 US dance 2 US alt. 15 | [Warner 27738 (Sire)] written by Vince Clarke & Andy Bell |
| 42. | 05/1988 | | 174
 | US 12 UK 21 US rock 3 | co-produced by Bernard Edwards [Warner 27927] written by Rod Stewart & Andy Taylor |
| 43. | 02/1988 | | 174
 | US 20 US rock ✫1 | [CBS Associated 4-07720] written by Henry Lee Summer |
 | 44. | 12/1988 | | 171
 | US 24 US rock ✫1 | written by David Paul Bryant, Steve Dubin & Adrian Gurvitz |
| 45. | 05/1988 | | 169
 | UK 11 US rock 16 US alt. 7 | written by Fiachna O'Braonain, Liam Ó Maonlaà & Peter O'Toole |
 | 46. | 07/1988 | | 169
 | US 4 UK 77 US AC 32 US rock 8 | [Columbia 07965 (Epic)] written by Otis Blackwell & Elvis Presley |
 | 47. | 07/1988 | | 168
 | US 3 US dance ✫1 US alt. 10 | [Tommy Boy 27826] written by Paul Robb & Kurt Harland |
 | 48. | 12/1988 | | 164
 | UK 11 US dance 2 US alt. 3 | written by Gillian Gilbert, Peter Hook, Stephen Morris & Bernard Sumner |
 | 49. | 02/1988 | | 163
 | UK 5 US alt. 3 | [RCA 8682] written by Paul Court, Steve Dullaghan & Tracy Tracy |
| 50. | 05/1988 | | 163
 | US 34 US rock ✫1 | [Warner 27891] written by Michael Anthony, Sammy Hagar, Eddie Van Halen & Alex Van Halen |
 | 51. | 04/1988 | | 163
 | US ✫1 UK 9 US AC 8 | [Atlantic 89109] written by Debbie Gibson |
| 52. | 11/1988 | | 160
 | US 69 US AC 11 US rock ✫1 | as Crosby, Stills, Nash & Young [Atlantic 7-88966] written by Stephen Stills & Neil Young |
| 53. | 01/1988 | | 160
 | US 15 US AC 37 US rock 2 | [A&M 2992] written by Sting |
 | 54. | 01/1988 | | 157
 | US 7 UK 53 US AC 36 US rock 10 | [Chrysalis 43201] written by Iva Davies & John Oates |
| 55. | 06/1988 | | 156
 | UK 6 US alt. 4 | with Chrissie Hynde written by Eddie Hinton & Donnie Fritts |
 | 56. | 10/1988 | | 156
 | US 45 UK 21 US AC 30 US rock 2 | [Wilbury 27732] written by George Harrison, Jeff Lynne, Bob Dylan, Tom Petty & Roy Orbison |
 | 57. | 09/1988 | | 155
 | UK 35 US alt. ✫1 | written by Julian Cope |
| 58. | 07/1988 | | 154
 | US rock ✫1 | [Warner 27728] written by Paul Barrere & Craig Fuller |
 | 59. | 03/1988 | | 154
 | US 24 US rock 2 | [Arista 9673] written by Steve Kilbey & Karin Jansson |
 | 60. | 06/1988 | | 152
 | US 66 UK ✫1 US dance 16 US alt. 17 | as The Timelords written by R. Grainer, G. Glitter & The Timelords |
| 61. | 10/1988 | | 152
 | US 60 US rock ✫1 | produced by Mark Knopfler [Warner 27709 (Reprise)] written by Randy Newman |
| 62. | 02/1988 | | 152
 | US 14 UK 96 US rock 3 | as John Cougar Mellencamp written by John Mellencamp |
 | 63. | 09/1988 | | 151
 | US ✫1 UK 25 US AC 5 | [Elektra 69385] written by John Phillips, Scott McKenzie, Mike Love & Terry Melcher |
 | 64. | 06/1988 | | 151
 | US 30 UK 52 US AC 9 US rock 2 | [Polydor 887600] written by Justin Hayward |
 | 65. | 07/1988 | | 150
 | UK 75 US alt. ✫1 | written by Richard Butler, John Ashton & Tim Butler |
 | 66. | 03/1988 | | 147
 | US 5 UK 91 US AC ✫1 US rock 18 | [Atlantic 89101] written by Mick Jones [Foreigner] |
| 67. | 08/1988 | | 147
 | US 74 US rock ✫1 | [Columbia 07980] written by Tommy Conwell & M. Rauer |
| 68. | 03/1988 | | 145
 | US 92 US rock ✫1 | [Capitol 44150 (Enigma)] written by Pat DiNizio |
| 69. | 10/1988 | | 141
 | UK 41 US dance 37 US alt. 2 | written by Siouxsie & the Banshees |
 | 70. | 09/1988 | | 141
 | US ✫1 UK 77 US AC ✫1 | [Warner 27766 (Reprise)] written by Diane Warren |
 | 71. | 05/1988 | | 141
 | UK 51 US dance 45 US alt. ✫1 | written by Mick Jones [The Clash], Don Letts & Greg Roberts |
 | 72. | 04/1988 | | 140
 | US 80 UK ✫1 US AC 31 US country 85 US alt. 23 | [BRIT Awards Best British Single 1989] [RCA 8789] written by Mark Nevin |
 | 73. | 01/1988 | | 137
 | US 2 UK 50 US AC 2 US rock 41 | [EMI 50113] written by Richard Marx |
| 74. | 10/1988 | | 136
 | US 59 US dance ✫1 US alt. 3 | written by Heiko Maile, Marcus Meyn & Oliver Kreyssig |
 | 75. | 10/1988 | | 135
 | US 31 UK 5 US dance 18 US alt. 14 | featuring Tom Jones written by Prince |
| 76. | 01/1988 | | 135
 | US 8 US rock 18 | [Atlantic 89126] written by Mike Tramp & Vito Bratta |
| 77. | 11/1988 | | 134
 | US rock 22 US alt. 6 | |
| 78. | 03/1988 | | 133
 | US 84 UK 76 US rock 3 | [Es Paranza 7-99333] written by Phil Johnstone & Robert Plant |
| 79. | 08/1988 | | 133
 | UK 16 US rock 20 US alt. 11 | [Warner 27737 (Reprise)] written by Stuart Adamson |
| 80. | 11/1988 | | 131
 | US 9 US dance 5 US R&B 64 US alt. 15 | [Warner 27736 (Tommy Boy)] written by Paul Robb |
| 81. | 04/1988 | | 130
 | US 6 UK 35 US rock 19 | [Enigma 44145] written by Bobby Dall, C.C. DeVille, Bret Michaels, Rikki Rockett & Bombilla (Jordi Carretero) |
| 82. | 05/1988 | | 129
 | US 35 UK 88 US AC 7 US rock 5 | [RCA 8678] written by Bruce Hornsby & John Hornsby |
 | 83. | 05/1988 | | 128
 | US 8 UK 46 US rock 20 | as Joan Jett & the Blackhearts written by Joan Jett & Desmond Child |
 | 84. | 09/1988 | | 128
 | US 18 UK 7 US dance 5 US alt. 22 | [EMI-Manhattan 50161] written by Neil Tennant & Chris Lowe |
| 85. | 12/1988 | | 127
 | UK 32 US alt. 3 | written by Mike Scott & Steve Wickham |
 | 86. | 12/1988 | | 127
 | US 13 UK 89 US rock 9 | [Epic 34-68611] written by Vernon Reid, Will Calhoun, Corey Glover & Muzz Skillings |
 | 87. | 06/1988 | | 127
 | US 12 UK 11 US dance 4 US alt. 22 | [Warner 27844 (Sire)] written by Vince Clarke & Andy Bell |
| 88. | 12/1988 | | 123
 | US 4 UK 49 US AC 3 US rock 50 | co-produced by Bernard Edwards [Warner 27729] written by Simon Climie & Dennis Morgan |
| 89. | 09/1988 | | 122
 | UK 84 US dance 28 US R&B ✫1 US rock 43 US alt. 5 | written by Tyrone Downie & Ziggy Marley |
| 90. | 12/1988 | | 122
 | US 52 US rock 50 US alt. 5 | [US chart position is for Hot 100 Airplay charts] [album cut] written by Lou Reed |
 | 91. | 05/1988 | | 121
 | US ✫1 US AC 3 | [EMI-Manhattan 50106] written by Richard Marx |
| 92. | 02/1988 | | 121
 | US rock 2 | [Warner 27825] written by David Lee Roth & Steve Vai |
 | 93. | 01/1988 | | 121
 | US 3 UK 19 US AC 16 US dance 44 | [Atlantic 89129] written by Debbie Gibson |
 | 94. | 08/1988 | | 120
 | US 12 UK 57 US AC 3 US rock 13 | co-produced by Bernard Edwards [Warner 27796] written by Jim Cregan, Kevin Savigar, Bob Dylan & Rod Stewart |
 | 95. | 12/1988 | | 120
 | US 22 UK 9 US dance ✫1 US alt. 24 | written by Nick Rhodes, Simon Le Bon & John Taylor |
| 96. | 10/1988 | | 120
 | US alt. 2 | written by Elizabeth Fraser, Robin Guthrie & Simon Raymonde |
| 97. | 10/1988 | | 119
 | US 26 US rock 6 | [Polydor 887 814-7] written by Ivan Neville |
| 98. | 11/1988 | | 119
 | US 63 UK 80 US rock 3 | [Atlantic 7-88990] written by Mike Rutherford & B. A. Robertson |
 | 99. | 10/1988 | | 119
 | US rock 8 US alt. 28 | written by Bono, The Edge, Adam Clayton & Larry Mullen Jr. |
 | 100. | 04/1988 | | 118
 | US 3 UK 81 US AC 2 US R&B 13 | [Arista 9685] written by Daryl Hall |